Приймаються статті для публікації в № 2 (42)/2022
rn Міжнародного науково-практичного журналу "Товари і ринки" з технічних та економічних наук 



Автор: sveta on . Posted in 2021_03(39)

Cite as APA style citation
Antiushko D. Vitamin value of the gerodietetic product for enteral nutrition. International scientific-practical journal "Commodities and markets". 2021. N 3. P. 115-125.


UDC 641.1:613.2.032.33   DOI: https://doi.org/10.31617/tr.knute.2021(39)09
E-mail:  Ця електронна адреса захищена від спам-ботів. вам потрібно увімкнути JavaScript, щоб побачити її.
ORCID: 0000-0002-4135-6439
  Candidate of Technical Sciences, Associate Professor, Associate Professor
at the Department of Commodity Science, Safety and Quality Management,
Kyiv National University of Trade and Economics
19, Kyoto str., Kyiv, 02156, Ukraine


Background. The analysis of the current demographic structure of the world and Ukrainian population gives reasons to state a rather significant increase in the number of older age groups representatives. At the beginning of 2021, the total number of people over 60 in Ukraine is more than 10 million and is 24.44 %. According to the rate of population aging and the general dynamics of this indicator, Ukraine ranks 10-th in world rankings
In order to create appropriate conditions to meet the nutritional needs, especially of elder aging groups representatives, including with increased physical and emotional loads, during periods of diseases and injuries treatment, primarily somatic, and reha­bilitation after them, a Ukrainian gerodietetic dry powdery product for enteral nutrition has been developed
The aim of the work is to research the vitamin value of gerodietetic dry soluble product for enteral nutrition and to analyze the average satisfaction level of the recom­mended daily requirement for the elderly persons in presented vitamins after product’s consumption in a ready liquid form.
Materials and methods. The research’s object was the developed gerodietetic dry soluble product for enteral nutrition. Dry soluble product for enteral nutrition Peptamen, produced by the Nestle company (Switzerland), was selected as a control sample.
The following methods were used to research the vitamin value: high-performance liquid chromatography using the liquid chromatograph "Lumachrom" with a chromatographic column and a pre-column, filled with an inverted-phase sorbent "Kromasil C18", and spectrophotometric, using a spectrophotometer "Specord 210".
While holding the research five-fold replicate experiments and three-fold analyzes were used. Mathematical and statistical processing of the results was performed using a computer in MS Excel. The determined reliability of the deviation of the obtained results does not exceed 0.03.
Results. The obtained experimental results allow to state that the addition of whey protein concentrate into the developed gerodietetic powdery product for enteral nutrition contributed to the provision of high biological value, in particular to increase the content of niacin, pantothenic acid, riboflavin, retinol, thiamine, pyridoxine, ascorbic acid. Additional enrichment of the product by the β-carotene (taking into account its corresponding retinol equivalence), thiamine, riboflavin, pyridoxine and calciferol allowed to increase the vitamin value of the product significantly.
It was established, that consumption (usage) of the developed gerodietetic product for hereditary purposes significantly contributes to the intake of retinol (including β-carotene) – the daily requirement is achieved by almost 83.45 %, thiamine – by 66.53 %, riboflavin – by 2.94 %, pyridoxine – by 80.84 %, ascorbic acid – by 25.09 %, less for niacin – by 5.89 %, pantothenic acid – by 19.16 %, folic acid – by 10.67 % and almost does not meet the needs of cyanocobalamin – only 0.06 %, calciferol – by 0.04 %, other vitamins.
Conclusion. The developed gerodietetic dry soluble product for enteral nutrition is characterized by increased vitamin value and rather high level of ensuring the gene­ralized daily needs of persons belonging to the older age category in vitamins, in par­ticular with increased physical and emotional loads, diseases and injuries, including somatic, due to the consumption of 100 g of dry soluble product in liquid prepared form.
The prospect of further research is the clinical analysis of vitamins, that are presented in the developed product, metabolic absorption level and a more detailed study of product’s consumer properties.
Keywords: vitamin value, gerodietetic product for enteral nutrition, vitamin enrichment, fat- and water-soluble vitamins, antioxidants, satisfaction level, recom­men­ded daily requirement.


  1. Ageing and health. World Health Organization. Retrieved from https://www.who.int/ news-room/fact-sheets/detail/ageing-and-health [in English].
  2. World Population Ageing 2017 Highlights. Retrieved from https://www.un.org/en/ development/desa/population/publications/pdf/ageing/WPA2017_Highlights.pdf [in English].
  3. Rozpodil postijnogo naselennja Ukrai’ny za stattju ta vikom na 1 sichnja 2021 roku [Distribution of the permanent population of Ukraine by sex and age as of January1, 2021]. Retrieved from http://www.ukrstat.gov.ua/druk/publicat/kat_u/2021/zb/06/zb_rpn21_ue.pdf [in Ukrainian].
  4. Ukrai’na – sered svitovyh lideriv za tempamy "starinnja" naselennja [Ukraine is among the world leaders in the rate of "aging" of the population]. Retrieved from https://www.ukrinform.ua/rubric-society/2391914-ukraina-sered-svitovih-lideriv-za-tempami-starinna-naselenna.html [in Ukrainian].
  5. Global Clinical Nutrition Products Market 20202025 – Shift Towards Home Care Boosts Demand. Retrieved from https://www.businesswire.com/news/home/20200521005460/ en/Global-Clinical-Nutrition-Products-Market-2020-2025---Shift-Towards-Home-Care-Boosts-Demand---ResearchAndMarkets.com [in English].
  6. Enteral Nutrition Market Research Report by Product, by Application, by End User, by Distribution Channel – Global Forecast to 2025 – Cumulative Impact of COVID–19Retrieved from https://www.globenewswire.com/fr/news-release/2021/01/14/2158477/0/ en/Enteral-Nutrition-Market-Research-Report-by-Product-by-Application-by-End-User-by-Distribution-Channel-Global-Forecast-to-2025-Cumulative-Impact-of-COVID-19.html [in English].
  7. Worldwide Enteral Nutrition Industry to 2027 – Growth in Incidence of Chronic Diseases is Driving the MarketRetrieved from https://www.businesswire.com/ news/home/20210611005334/en/Worldwide-Enteral-Nutrition-Industry-to-2027---Growth-in-Incidence-of-Chronic-Diseases-is-Driving-the-Market---ResearchAndMarkets.com [in English].
  8. Antiushko, D. (2020). Evaluation of gerodietetic product’s for enteral nutrition protein value. Journal of chemistry and technologies, 28 (2), 161-167 [in English].
  9. Europe Enteral Feeding Formulas Market Research Report – Segmented By Product, Stage, Application, End User and Country (UK, France, Spain, Germany, Italy, Russia, Sweden, Denmark, Switzerland, Netherlands, Turkey, Czech Republic and Rest of Europe) – Industry Analysis, Size, Share, Trends and Growth Forecast (2021 to 2026). Retrieved from https://www.marketdataforecast.com/market-reports/europe-enteral-feeding-formulas-devices-market [in English].
  10. Antiushko, D. (2021). The elements composition of gerodietetic product for enteral nutrition. Mizhnarodnyj naukovo-praktychnyj zhurnal "Tovary i rynky" – Interna­tional Scientific and Practical Journal "Commodities and Markets", 2 (38), 63-69. DOI: 10.31617/tr.knute.2021(38)06 [in Ukrainian].
  11. Strasser, B., Pesta, D., Rittweger, J., Burtscher, J., & Burtscher, M.(2021). Nutrition for Older Athletes: Focus on Sex-Differences. Nutrients, 13 (5), 1409 [in English].
  12. Azzolino, D., Saporiti, E., Proietti, M., & Cesari, M. (2020). Nutritional Considerations in Frail Older Patients with COVID–19. J Nutr Health Aging, 24 (7)696-698[in English].
  13. Ekmekcioglu, C.(2020). Nutrition and longevity – from mechanisms to uncertainties. Critical Reviev Food Science Nutrition, 603063-3082 [in English].
  14. Kritchevsky, S. B. (2016). Nutrition and Healthy Aging. J Gerontol A Biol Sci. Med Sci, 71, 1303-1305 [in English].
  15. Antjushko, D. P., & Karpenko, P. O. (2016). Perspektyvy vykorystannja produktiv dlja enteral’nogo harchuvannja v gerodijetychnij praktyci. Mezhdunarodnyj nauchno-prakticheskij zhurnal "Problemy starenija i dolgoletija" – International scientific and practical journal "Problems of Aging and Longevity". Vol. 25, 2, 215-221 [in Ukrainian].
  16. Corella, D., Barragán, R., Ordovás, J., & Coltell, Ó. (2018). Nutrigenética, nutri­ge­nómica y dieta mediterránea: una nueva visión para la gastronomía (Nutrigenetics, nutrigenomics and Mediterranean diet: a new vision for gastronomy). Nutr Hosp3519-27 [in Spanish & in English].
  17. Ordovas, J. M., & Berciano, S. (2020). Personalized nutrition and healthy aging. Nutr Rev, 78 (12), 58-65 [in English].
  18. Gavalko, Ju. V., Romanenko, M. S., Synjeok, L. L., Fus, S. V., Gorobec’, L. V., Zhevaga, L. M. et al. (2016). Stan zabezpechenosti makro- i mikroelementamy u prak­tychno zdorovyh ljudej riznogo viku [The state of provision with macro- and micro­elements among almost healthy people of different ages]. Mezhdunarodnyj nauchno-prakticheskij zhurnal "Problemy starenija i dolgoletija". Vol. 25, 3-4, 266-278 [in Ukrainian].
  19. Prytul’s’ka, N., & Antjushko, D. (2016). Kryterii’ rozrobky harchovyh produktiv gerodijetychnogo pryznachennja [Criteria for the development of food products for herodietic purposes]. Mizhnarodnyj naukovo-praktychnyj zhurnal "Tovary i rynky" – International Scientific and Practical Journal "Commodities and Markets", 2, 83-92 [in Ukrainian].
  20. Johnson, K. A., Bernard, M. A., & Funderburg, K. (2002). Vitamin nutrition in older adults. Clin Geriatr Med, 18 (4)773-799 [in English].
  21. Prytul’s’ka, N. V., Karpenko, P. O., Antjushko, D. P., & Gavalko, Ju. V. Sumish dlja enteral’nogo harchuvannja gerodijetychnogo pryznachennja [Mixture for enteral nutrition for herodietic purposes]. Patent UA, N 116754 [in Ukrainian].
  22. Ames, B. N. (2018). Prolonging healthy aging: Longevity vitamins and proteins. Proc Natl Acad Sci U S A, 115 (43), 10836-10844 [in English].
  23. Simahina, G. O., & Naumenko, N. V. (2016). Harchuvannja jak osnovnyj chynnyk zberezhennja zdorov’ja naselennja [Nutrition as a major factor in maintaining the health of the population]. Mezhdunarodnyj nauchno-prakticheskij zhurnal "Problemy starenija i dolgoletija" – International scientific and practical journal "Problems of Aging and Longevity"Vol. 25, 2, 204-214 [in Ukrainian].
  24. Milk and milk products – Guidance on sampling. ISO 707:2008. Retrieved from https://www.iso.org/obp/ui/#iso:std:iso:707:en [in English].
  25. Infant formula and adult nutritionals – Determination of vitamin E and vitamin A by normal phase high performance liquid chromatography. ISO 20633:2015. Retrieved from https://www.iso.org/obp/ui/#iso:std:iso:20633:ed-1:v1:en [in English].
  26. Infant formula and adult nutritionals – Determination of vitamin C by (ultra) high performance liquid chromatography with ultraviolet detection ((U)HPLC-UV). ISO 20635:2018. Retrieved from https://www.iso.org/obp/ui/#iso:std:68604:en [in English].
  27. Dried skimmed milk – Determination of vitamin D content using high-performance liquid chromatography. ISO 14892:2002. Retrieved from https://www.iso.org/obp/ui/#iso:std:iso:14892:ed-1:v1:en [in English].
  28. Infant formula and adult nutritionals – Simultaneous determination of total vitamins B1, B2, B3 and B6 – Enzymatic digestion and LC-MS/MS. ISO 21470:2020. Retrieved from https://dgn.isolutions.iso.org/obp/ui#iso:std:iso:21470:ed-1:v1:en [in English].
  29. Food products – Guidance on how to express vitamins and their vitamers content. ISO/TR 23304:2021. Retrieved from https://www.iso.org/obp/ui/fr/#iso:std:iso:tr:23304:ed-1:v1:en [in English].
  30. Infant formula and adult nutritionals – Determination of vitamin B12 by reversed phase high performance liquid chromatography (RP-HPLC). ISO 20634:2015. Retrieved from https://www.iso.org/obp/ui/#iso:std:iso:20634:ed-1:v1:en [in English].
  31. Palm oil – Determination of the deterioration of bleachability index (DOBI) and carotene content. ISO 17932:2011. Retrieved from https://www.iso.org/obp/ui/ #iso:std:54401:en [in English].